Mitochondria are well-known energy providers in our body cells, but research shows that they have many more functions. Scientists discovered that mitochondria may play an important role in the ageing process and fertility. This could open up new avenues to better understand and influence ageing.
A recent study focuses on a gene that regulates the distribution of mitochondria. In older mice, the activity of this gene decreases, which is linked to reduced fertility. This indicates that mitochondria can directly influence the ability to have children, in addition to the already known damage to the DNA in the cell nucleus that also plays a role.
The study investigates how this mechanism works, with the aim of gaining insight into human fertility problems. As they age, women find it harder to have children and more frequently encounter fertility issues. By better understanding how mitochondria contribute to this decline, new treatments could potentially be developed in the future.
Furthermore, this discovery is relevant to the general ageing process. Because mitochondria play a role in many organs, research into their function can help in developing therapies that preserve the quality of cells and organs for longer. This can contribute to a healthier and more active life in later years.
These findings underline how important mitochondria are for healthy ageing and fertility. They offer a promising new direction for research into long-term vitality.
Source: Buck Institute
