Researchers have created a comprehensive map of senescent cells in the human body. Senescent cells, also known as zombie cells, are cells that stop dividing but do not die. These cells accumulate as we get older and play an important role in the ageing process and age-related diseases.
Using new techniques, it has become clear that senescent cells comprise various types, depending on the cell type and location in the body. This insight helps to better understand how senescence contributes to ageing and which cells are most harmful to our health.
There are medicines, called senolytics, that can selectively clear out these cells. In animal studies, removing some of the senescent cells led to significant health improvements and restoration of bodily functions. In humans, however, research into and application of these medicines are still in their infancy.
This new atlas provides an important basis for follow-up research into effective treatments that can slow down the ageing process. This could ultimately help to promote healthy ageing by reducing the harmful effects of senescent cells.
Source: Reason
