Naked mole-rat microbiomes barely change with age

Naked mole rats are remarkable little animals that live much longer than mice of the same size. They can live for decades, whereas a mouse typically only lives for a few years. Furthermore, these animals rarely get diseases such as cancer and remain healthy and active into old age.

Researchers looked at the bacteria in the guts of these mole rats. In humans and mice, this gut microbiome changes as they get older. Those changes can lead to inflammation and a decrease in important substances that the body needs. In naked mole rats, however, this microbiome appeared virtually unchanged over the years.

The stable gut environment of these rodents may be related to their stronger immune system. This system keeps harmful bacteria in better balance, keeping the body healthy. A constant gut flora may also help to prevent inflammation and other signs of ageing.

This discovery contributes to our understanding of what can promote healthy ageing. It shows that a stable gut microbiome may play an important role in maintaining vitality and preventing age-related diseases.

For humans, this insight can help in finding ways to slow down the ageing process and stay healthy for longer.

Source: Reason