Researchers have discovered an important mechanism that plays a role in the ageing of stem cells in the bone marrow. These stem cells are essential because they are responsible for the production of red blood cells, white blood cells and platelets. As people age, these cells change, which can lead to a less effective immune system and blood-clotting problems.
The study shows that cellular stress contributes to ageing by impairing the function of the cells' power stations, the so-called mitochondria. This hinders the functioning of stem cells and can thus negatively affect the health of the blood and the immune system. By better understanding these stress responses, researchers can look for ways to slow down the ageing process.
According to the scientists, it is important not only to suppress the stress responses themselves, but also to look at the underlying damage that this stress causes. Thus, future treatments could focus on restoring cellular health instead of simply tackling the symptoms.
For everyone who wants to age healthily, this discovery is hopeful. It offers new starting points to potentially better prevent or treat problems with the immune system and blood supply at a later age.
Source: Reason
