Researchers have developed a new approach that can slow down ageing in mice by removing old and damaged cells, also known as senescent cells, from the body. These cells stop dividing and release inflammatory signals, which can damage tissue and organs in the long term. As we age, these types of cells accumulate, partly because the immune system becomes less effective at clearing them out.
The new therapy combines a special senolytic treatment, aimed at breaking down these old cells, with stem cell therapy. Stem cells have the ability to repair and renew damaged tissues. By first removing the harmful senescent cells, the stem cells can do their job better and stimulate the recovery process.
In a study involving mice that aged prematurely, this combination of techniques was shown to improve health and life expectancy. Although the research was conducted on mice rather than humans, it supports the idea that tackling ageing processes on multiple fronts can offer benefits. Reducing inflammation in particular plays an important role in healthy ageing.
This development shows that tackling old cells and stimulating tissue repair can contribute to better health at a later age. It is a promising step towards treatments that can reduce the negative effects of ageing.
Source: Reason
