Stem cell therapy is a promising approach to counter age-related complaints and degenerative disorders. Scientists are focusing primarily on improving older stem cells from the patients themselves so that these can assist more effectively in tissue repair. This process of ‘rejuvenation’ could restore the quality and function of the cells.
An important aspect of this research is the use of senolytics. These are substances that help clear away worn-out or damaged cells. They are seen as practical and affordable means to improve stem cells before they are used in treatments. This is in contrast to more complex methods such as ‘epigenetic reprogramming’, a technique that is not yet ready for everyday application in clinics.
Epigenetic reprogramming involves partially reverting cells to a younger state through changes in the way genes are read. Although promising, this method still requires a great deal of time and expertise before it can be widely applied. Therefore, for the time being, the focus is mainly on simpler and proven strategies such as senolytics.
These developments are important for people who want to age healthily, as they increase the likelihood that damaged tissues can repair themselves better. Stem cell therapies can thus contribute to a better quality of life in old age.
Source: Reason
