Researchers have discovered that changes in epigenetic clocks over a longer period provide valuable information about our health and lifespan. An epigenetic clock measures how fast our body is ageing based on chemical changes in the DNA. Until now, it was difficult to properly interpret these clocks for individual predictions. New research shows that not a single measurement, but rather the trajectory of the clock over multiple years is important.
This development is important because keeping track of changes in that clock can help predict how quickly someone ages biologically. Biological age gives a better picture of health than just the number of years lived. By taking repeated measurements in the same person, a clearer picture of the ageing process emerges. In the future, this could contribute to better advice and treatment methods to stay healthy for longer.
The use of machine learning plays a major role in the analysis of large datasets to develop these age clocks. In doing so, patterns are sought in biological information from people of various ages. Although this works well for groups, it remains difficult to make accurate predictions for individuals. Long-term studies can improve this and thus help in developing personalised insights.
This research shows that measuring changes in the epigenetic clock over time can be a good predictor of the risk of disease and death. This aligns with the need for reliable techniques to better understand and support healthy ageing. By measuring more frequently and tracking how the body adapts, it may be possible in the future to better slow down ageing and improve the quality of life.
These findings are relevant to anyone consciously engaged in healthy ageing. It demonstrates that regular health measurements and new technologies can help to gain a better grip on one's own biological ageing process. In this way, science can contribute to the prolonged maintenance of vitality and enjoyment of life.
Source: Reason
