Metformin is primarily known as a medication for type 2 diabetes and metabolic syndrome. This drug is also being researched for its potential to slow down the ageing process. Researchers are investigating whether metformin can act as a so-called ‘geroprotective’ agent to help improve lifespan and health in later life.
However, the research into metformin as an anti-ageing agent is not yet conclusive. Whilst animal studies show mixed results, there are also doubts about the quality of the human studies. Newer studies mostly show little evidence that metformin actually reduces the risk of death or prolongs lifespan.
Alongside metformin, rapamycin is mentioned as a potentially more effective agent. This agent appears to work better at slowing down ageing in some studies. It makes it clear that the search for medicines that promote healthy ageing is still very much ongoing.
It is important to understand that metformin is a medicine that affects blood sugar and cannot simply be used without medical supervision. Research into agents for ‘healthy ageing’ is complex and requires much more evidence before they can be widely used.
For people who want to age healthily, a healthy lifestyle currently remains the best choice to reduce the risk of diseases of old age and to remain vital for longer.
Source: Reason
