Researchers have discovered that accelerated aging of the epigenome in the forties is associated with a loss of memory function at a later age. The epigenome is a layer of chemical markers on DNA that can influence the activity of genes. Epigenetic age is a measure to determine how quickly a person’s biological aging progresses, independent of the calendar age.
The memory problem that stands out most here is prospective memory, the ability to perform planned tasks. This form of memory is particularly affected by the damage that aging causes to brain cells. The research shows that a higher biological age in middle age may indicate more memory problems around the age of 50 or 60.
The study used data from a large population group that examined the relationship between epigenetic age and self-reported memory problems. Although the study has limitations in terms of size and measurement methods, it emphasizes the role of early signals in midlife as predictors of later cognitive decline.
This is important because it provides insight into how early biological changes in the DNA can contribute to healthy aging. By paying attention to these signals in a timely manner, it may be possible to intervene earlier to limit or delay memory loss.
Source: Reason
