Scientists have developed a new method that measures the amount of harmful, aged cells in the body. These cells, also known as senescent cells, no longer divide and release substances that can cause inflammation and tissue damage. The new biomarker, called SASP Score, combines these harmful substances into a single measurement that can be determined through a simple blood test.
Measuring these substances is complicated because they consist of many different proteins that are interconnected in complex ways. Therefore, the researchers used an advanced computer program that can analyze this complex data using artificial intelligence. This creates a reliable overview of the total amount of these aged cells in the body.
The SASP Score appears to be associated with various signs of aging, such as reduced strength and fitness, and increases the risk of age-related diseases such as dementia and kidney problems. People with a high score also have a greater chance of dying. Interestingly, regular exercise can help to counteract the increase in these harmful cells.
This new measure provides more insight into the aging process and can help assess the health and effectiveness of lifestyle interventions. Especially for people who want to become healthier as they age, this can be a valuable tool.
Source: Josh Conway
