Researchers have discovered that the INDY gene plays an important role in maintaining a healthy gut in fruit flies. This gene is linked to a longer lifespan. By enhancing the activity of INDY, the flies appeared to suffer less from ageing problems in their gut. This helps them stay alive longer and healthier.
Gut health is a crucial factor in ageing. As humans and animals age, the composition of gut bacteria changes. Beneficial bacteria decrease, whilst bacteria that can cause inflammation increase. As a result, the intestinal wall can become damaged and more harmful substances are absorbed into the body, which places a burden on the body.
In fruit flies, preventing these changes in the gut flora appears to be able to delay ageing. The INDY gene helps to maintain the balance in the gut bacteria and thereby limit inflammation. This has positive consequences for the overall health and lifespan of the animals.
These insights highlight the importance of a healthy gut microbiota in ageing. It can also help people to find ways in which lifestyle or diet can support this process and thereby contribute to better health at an older age.
Good gut health is therefore essential for a long and vital life.
Source: Reason
