New research shows that the APOE2 gene has a protective effect on the brain. This gene appears to reduce damage to the DNA of brain cells and helps neurons recover better from stress. As a result, APOE2 may contribute to longer brain health.
ADP unravels why some people are less susceptible to Alzheimer's. Alzheimer's is a disease in which brain cells slowly die off, leading to memory loss and problems with thinking. Genes such as APOE play an important role in this. While the APOE4 gene increases the risk of Alzheimer's, the APOE2 gene actually provides protection.
Protecting the DNA in brain cells is essential, because damaged DNA can lead to the death of neurones. Thanks to this protection, the brain can continue to function properly for longer. This research could inspire new treatments that mimic the action of APOE2, which is especially valuable for people with a higher genetic risk of Alzheimer's.
Healthy ageing is not only about preventing disease, but also about maintaining well-functioning brains. Understanding how APOE2 works helps to better comprehend and support healthy brain ageing.
Source: Original article
