As we grow older, the number of worn-out cells in our bodies increases. These so-called senescent cells stop dividing and accumulate in tissues. This process plays a major role in the decline of bodily functions in old age. Stem cells, which produce new healthy cells, consequently have less and less room and are less able to do their job.
Stem cells normally ensure the repair and renewal of tissues. As these cells become less active, the body's ability to heal itself and stay healthy decreases. Research in mice indicates that if senescent cells are selectively removed, the regenerative capacity of tissues improves and signs of ageing are reduced.
This insight leads to hope for new treatments that can slow down ageing. By tackling senescent cells, stem cells can function better again, which can positively influence health in old age. The research also helps to better understand why certain age-related ailments arise and how they might be prevented.
For those interested in healthy ageing, this shows that maintaining healthy stem cells is important. The focus on cell renewal and the removal of worn-out cells can contribute to better health and mobility in later life.
Source: Reason
