New strategies focus on ageing and cellular senescence

The search for ways to counteract ageing is increasingly focusing on two key aspects: the decline in cell function and changes in our metabolism. Ageing is caused by a complex process in which cells begin to function less well and the body processes energy less efficiently. As a result, diseases such as memory problems, diabetes and cardiovascular disease occur more frequently at a later age.

Scientists distinguish two main groups of approaches in this regard. The first focuses on removing or reducing “old” cells, also known as senescent cells. These cells stop dividing and can release harmful substances that damage the surrounding tissue. The second group of treatments attempts to improve the body's metabolic process, so that the cells can function better and the body remains healthier.

Although this classification is useful, it is recognised that ageing is an interplay of many processes. Alongside cellular ageing and metabolism, other factors also play a part, such as inflammation and DNA damage. It therefore remains important to carry out more research in order to find even more effective treatment methods that can slow down the ageing process.

For everyone who is growing older, it is good to know that there are increasingly more opportunities to reduce age-related health problems. These developments can contribute to a better quality of life as we get older.

Source: Reason