Mitochondria are often known as the powerhouses of our cells. They supply the energy needed for all kinds of bodily functions. However, new research shows that mitochondria do much more than just supply energy. They also appear to play a key role in the ageing process and in fertility issues.
A researcher is investigating a protein involved in the division of mitochondria in cells. In older mice, this protein decreased, and at the same time they had difficulty reproducing. This points to a link between weakened mitochondrial function and reduced fertility. It is an important discovery because the research focuses on a gene that regulates the health of mitochondria from the cell nucleus.
It has been known for some time that DNA damage in the cell nucleus affects fertility, such as premature menopause. This new study focuses specifically on the mitochondrial aspect of this, an area that has been little researched. The insights could help to develop new treatments that maintain fertility for longer.
The findings are not only important for reproduction, but also provide new information on the ageing process in general. Mitochondria function less well as we get older, but why that happens was not yet clear. The research could be a step towards therapies that address mitochondrial problems in ageing organs.
For anyone who wants to age healthily, this knowledge can help to gain more control over maintaining vitality and longevity.
Source: Buck Institute
