As we grow older, our teeth change too. They become more brittle and can damage more quickly because the cells in the dental tissue do not do their job as well. This process is still relatively new in scientific research, but it is clear that old age plays an important role in the decay of teeth.
Researchers have discovered that the decrease in a certain protein, NFATC1, in dental tissue cells contributes to this ageing. This protein is important for maintaining the strength and structure of teeth. When this protein is less present, the dental tissue is less able to repair itself.
A major cause of the loss of NFATC1 is so-called senescent cells. These are old cells that no longer function properly and can release harmful substances. New treatments, known as senolytic therapies, can clear away these senescent cells. As a result, the negative effect of ageing on the teeth is reduced.
These findings offer hope that in the future we will be able to better protect teeth against the signs of ageing. Maintaining teeth properly contributes to better oral health and can help reduce discomfort and pain at a later age.
This research is important because strong and healthy teeth contribute to a pleasant and healthy life as we grow older.
Source: Reason






