More mutations in healthy cells increase the risk of cancer

Cancer mainly occurs in older age. This is due to various factors, including the decline in the functioning of our immune system. This system normally protects us against cancer cells. Additionally, older people accumulate more damage in their cells, which increases the risk of cancer. Scientists call these damage somatic mutations.

New research shows that not only cancer cells themselves, but also healthy cells from cancer patients contain more of these mutations. Especially stem cells, which reproduce constantly, can pass on such mutations to new cells in the body. This increases the chance that a combination of mutations will occur in a particular area, which could cause cancer.

The concept of somatic mosaic formation is important in this context. This means that groups of cells in the body can have different mutations. As we age, this mosaic formation increases. The more mutations accumulate, the greater the chance of the formation of cancer cells. Good care and a healthy lifestyle can help maintain the immune system strongly and limit the effects of mutations.

For those who want to become healthier as they age, it is important to understand that the body undergoes changes over the years that increase the risk of cancer. By paying attention to lifestyle and regular check-ups, we can better manage these risks.

Source: Reason