As we age, our immune system changes as well. Scientists have found that these changes play an important role in the development of bone thinning (osteoporosis) and joint wear and tear (arthrosis). This goes beyond just age itself. As we age, the immune system becomes less well-balanced, which often leads to inflammation becoming more prolonged and more harmful.
An important aspect of this is the accumulation of ‘old’ or damaged cells, which are called senescent cells. Normally, the immune system removes these cells, but as we age, this clearance process becomes less effective. As a result, these cells accumulate and release harmful substances that damage bone and joint tissue. This interaction between the aging immune system and the cells accelerates the process of bone and joint breakdown.
This insight provides a broader picture of why bone loss and joint wear and tear can occur together and be difficult to stop. The relationship between the immune system and the buildup of damaged cells shows that it is not a single cause, but a complex interplay of processes that affect each other. This can also explain why traditional treatments sometimes have limited effect.
For those who want to become healthier with age, it is important to support the immune system as best as possible. Healthy nutrition, sufficient exercise, and avoiding prolonged inflammation can all contribute to a better functioning immune system. This may reduce the risk of serious bone and joint disorders.
Source: Reason
